The only reported side-effects from using GcMAFplus® are mild detox-like symptoms such as a runny nose, fatigue, nausea and restlessness as the immune system adjusts. These are very rare and usually associated with higher strength doses in the first few days of use. If you experience such effects you may stop using the product/s for a few days until they recede and then begin use again. If you are concerned about anything with our products, please consult with your doctor or registered physician.