Transdermal Creams
Buy GcMAFplus® immunotherapy products shipped worldwide.
All GcMAFplus® products are made in an Australian GMP ISO22716 certified laboratory and tested to be 100% bioidentical to GcMAF naturally produced in the body.

Be aware that the stomach acids will destroy any benefit of GcMAF in the digestion process. Taken orally, GcMAF is sensitive to acidic environments like the stomach, and the acidic conditions can denature and break down the protein before it can exert its beneficial effects.
Why Oral GcMAF Products, Lollies, Yoghurts, or Powders Are Not Effective
GcMAF is a complex protein molecule that must reach the immune system intact to exert its biological effects. When taken orally, it encounters the acidic environment of the stomach, where digestive enzymes and gastric acid rapidly break down protein structures. This process renders GcMAF inactive before it can reach the bloodstream or immune cells.
Stomach Acid Destroys GcMAF
It is a well-established scientific fact that proteins ingested orally are denatured by stomach acid. This applies to GcMAF, which cannot survive the digestive tract intact. Products such as capsules, tablets, lollies, yoghurts, and powders — no matter what claims are made — are not viable delivery systems for GcMAF.
– Yoghurt is not GcMAF – and it does not activate GcMAF.
– Colostrum is not GcMAF – and it does not activate GcMAF.
– Sugar-based lollies and powders are not GcMAF, nor can they survive the digestive process to deliver GcMAF to the body.
– Capsules and tablets may contain ingredients labeled as “GcMAF,” but these are typically broken down by the stomach before they can be absorbed.
To be effective, GcMAF must be absorbed intact and delivered to the immune system. That is why professional-grade GcMAF products use sublingual or transdermal routes, which bypass the gastrointestinal tract and avoid the destructive effects of stomach acid.
The Difference Between Colostrum and GcMAF
Colostrum is not GcMAF. While colostrum is rich in immune-supportive components like immunoglobulins and lactoferrin, it does not contain or produce GcMAF.
GcMAF (Gc Macrophage Activating Factor) is derived from vitamin D-binding protein (also known as Gc protein). To produce GcMAF, this parent protein must undergo a precise enzymatic cleavage process that removes two sugar molecules, leaving the active GcMAF structure.
While colostrum can be used as the source material for extracting Gc protein in a laboratory setting, it does not remain in the final product. Professional extraction ensures zero colostrum or casein residues, resulting in a purified GcMAF protein.
Why Sublingual and Transdermal GcMAF Work
At GcMAFplus, we produce GcMAF in a certified GMP laboratory using non-fermentation, enzymatic methods to ensure purity and activity. Our products are delivered either:
– Sublingually (under the tongue), where absorption occurs directly into the bloodstream through mucous membranes, or
– Transdermally, using our proprietary Super Transdermal Absorption Technique, which transports GcMAF through the skin into the lymphatic system.
These methods allow the GcMAF molecule to remain intact and biologically active — something oral products simply cannot achieve.
Summary
If you’re being offered GcMAF in yoghurt, capsules, lollies, powders, or DIY kits — be cautious. These formats do not contain real, active GcMAF, and they cannot deliver it effectively to your immune system. Only lab-purified GcMAF, delivered via sublingual or transdermal routes, can bypass stomach acid and reach your immune system where it matters.