Transdermal and Sublingual are the best non-intrusive ways to administer GcMAF and optimize its benefits.

Transdermal and Sublingual: The use of our own proprietary blend formula facilitates the transport of GcMAF into the underlying layers, where it gains access to the lymphatic system. Once in the lymphatic system, GcMAF can interact with immune cells, especially macrophages, and activate them. Activated macrophages play a crucial role in identifying and eliminating harmful agents, pathogens and abnormal cells, thereby bolstering the immune system’s healing and defence mechanisms.

By directly working within the lymphatic system, our specialized transdermal GcMAF formula ensures targeted delivery and immune modulation. The GcMAF activation of macrophages enhances their ability to support the body in healing and defending against a wide range of health challenges.

This innovative approach allows individuals to experience the benefits of immune support without invasive procedures or systemic side effects. With our transdermal GcMAF creams, we empower the immune system to work efficiently and naturally, aiding the body in its healing journey and promoting overall well-being. Our commitment to excellence in formulation and dedication to cutting-edge science make us a leading provider of transdermal GcMAF, redefining immune health support for the better.

TRANSDERMAL

We have created a “Super Transdermal Absorption Technique” with a high concentration of Active Ingredients.

Advanced Transdermal GcMAF Delivery at GcMAFplus®

At GcMAFplus®, our transdermal GcMAF formulation stands apart from others on the market due to its scientifically engineered design and advanced absorption properties. We have invested heavily in research and development to create a unique, high-purity formula capable of efficient delivery through the skin and into the immune system.

Laboratory-Certified Purity — Not Colostrum-Based

While our GcMAF protein is enzymatically extracted from colostrum, it’s important to clarify: the final product contains no colostrum, no casein, and no milk residues. Colostrum acts solely as the protein source, not as an ingredient. During the purification process, advanced laboratory techniques are used to remove all residual material, resulting in pure, active GcMAF protein that is bioidentical to that produced in healthy individuals.

Scientifically Engineered Skin Penetration

It is often suggested that GcMAF, due to its molecular size and complex structure, cannot penetrate the skin. While this is generally true in conventional formulations, our team of formulation scientists has overcome this barrier using:

• Emulsification techniques

• Particle size reduction

• Lipophilic carrier enhancement

• pH optimization for dermal compatibility

These processes allow GcMAF to traverse the stratum corneum and reach the dermis, where lymphatic and immune cells reside. The result is a clinically relevant transdermal absorption pathway that allows GcMAF to be distributed systemically through the lymphatic system.

Super Transdermal Absorption Technique

Our proprietary Super Transdermal Absorption Technique is designed to:

• Enable delivery of high concentrations of GcMAF through the skin

• Maximize absorption into immune tissues

• Maintain stability and bioactivity of the protein throughout the process

This delivery system ensures therapeutic action where it matters most — at the level of macrophage activation and immune regulation.

High-Potency, Lipophilic Formulation

Each batch of GcMAFplus® cream is manufactured with a high concentration of active ingredients, carefully balanced for skin compatibility and therapeutic impact.

Our formula emphasizes lipophilic (fat-loving) compounds, which integrate more effectively with the skin’s natural lipid barrier than hydrophilic (water-based) alternatives. This strategy enhances bioavailability and cellular uptake beneath the epidermis.

Non-Fermented, GMP-Certified Manufacturing

We do not use fermentation in any part of our process. GcMAFplus is produced under GMP ISO22716-certified conditions using non-fermentation methods that preserve molecular integrity and therapeutic efficacy. Each step is controlled by qualified personnel to ensure sterility, potency, and purity.

In summary, GcMAFplus® transdermal cream is a professionally formulated, high-purity product designed to penetrate the skin barrier and deliver active GcMAF to the lymphatic system and immune cells. It is purified, potent, and laboratory-tested — with no fermentation, no colostrum, and no dairy content in the final product.

SUBLINGUAL

Sublingual GcMAF Delivery

Sublingual administration of GcMAF involves placing the solution under the tongue and holding it there for a brief period, allowing the GcMAF to absorb directly through the mucosal membranes into the bloodstream. This method bypasses the digestive system, avoiding degradation by stomach acids and enzymes, and ensures higher bioavailability.

The sublingual area is rich in capillaries and blood vessels, providing a fast and efficient route for systemic absorption. Once absorbed, GcMAF enters circulation and reaches the lymphatic system, where it can interact with immune cells — particularly macrophages — to stimulate immune activity.

Activated macrophages play a central role in identifying and destroying pathogens, abnormal cells, and inflammatory triggers. By initiating this response, GcMAF helps reinforce the body’s natural defence mechanisms.

Sublingual delivery offers several key advantages:

• Rapid absorption into systemic circulation

• Higher bioavailability compared to oral ingestion

• Non-invasive and easy to use, especially for patients avoiding injections

• Efficient lymphatic access to support immune modulation

At GcMAFplus, our sublingual sprays are formulated to deliver purified, high-potency GcMAF in a format that’s fast-acting, convenient, and clinically reliable. Sublingual and transdermal GcMAF offer two complementary, non-invasive options — both designed to activate immune responses without the risks or discomfort associated with injectable therapies.